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JOSEPH FRANCIS MURPHY, PH. D. PARTNER TELEPHONE: 215-567-2010.
EXTENSION 206
FAX: 215-751-1142
jmurphy@crbcp.com
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Dr. Murphy is a registered Patent Attorney and practices all aspects of patent prosecution, including patent reissue and reexamination proceedings. He has extensive experience in the prosecution of Inter Partes Reexaminations, and prosecution before the Board of Patent Appeals and Interferences. Dr. Murphy's practice also includes international patent prosecution and opinion work, including validity, invalidity, infringement and freedom to operate. He in experienced in diversified technologies, especially in the biotechnological, chemical, and pharmaceutical arts. Prior to joining the firm, Dr. Murphy worked for 6 years in the United States Patent and Traemark Office as a Biotechnology Patent Examiner. He has Full Signatory Authority and was a Master's Level Examiner. He was reponsible for examining patents involving cytokines, chemokines, G protien-coupled receptors, Ion channels, and other polypeptides. Dr. Murphy received his Ph.D. in Physiology from the University of Virginia in 1997. He did his post-doctoral fellowship at the A.I. DuPont Institute in the Epithelial Cell Biology Laboratory from 1997-1999. He served as a Post Doctoral Scientist for Message Pharmaceuticals, Inc. developing assays for secondary screening of compunds that target RNA. A graduate of George Washington University School of Law (2005), Dr. Murphy received his undergraduate degree in Biology from St. Joseph' University in 1989.
Pennsylvania
U.S. Patent and Trademark Office
U.S. Court of Appeals for the Federal Circuit
Member, American Intellectual Property Law Association
Member, Philadelphia Intellectual Property Law Association
Stevenson RW, Murphy JF, Clare TJ: Robot Inventors: Patently Impossible? Science 324 (5930), 1014-a (22 May 2009)
Stevenson RW, Murphy JF, Clare TJ: Robots and the Law: Will the Real Inventor Please Stand Up? E-Commerce Times. 28 April 2009.
Murphy JF: The Federal Circuit on Inherent Anticipation, Obviousness, and Claim Construction. Pennsylvania Bar Institute, PBI No. 2006-4403, pp. 274-292
Murphy JF: "Possible Role of Phosphorylation and Cytoplasmic Factors in the Regulation of Functionally Expressed GIRK/CIR Channels." Dissertation. May 1997.
Xu L, Murphy JF, Otero A de S: Participation of Nucleoside-diphosphate Kinase in Muscarinic K+ Channel Activation Does Not Involve GTP Formation. J. Biol. Chem. 271:21120-21125 (1996).
Murphy J, Kuznetsov A, Philipson LH, Szabo G: Single Channel Characteristics of a G-Protein Linked Epitope-tagged K+ Channel (GIRK1-cp) Expressed in Stably Transfected Mammalian Cells. Biophysical Journal 68(2):A354 (1995).
Philipson LH, Kuznetsov A, Toth PT, Murphy JF, Szabo G, Mal GH, Miller RJ: Functional Expression of an Epitope-tagged G-protein-coupled K+ Channel (GIRK1) . J. Biol. Chem. 270:14604-14610 (1995).
Murphy JF, Graber SG, Garrison JC, Szabo G: Recombinant G Protein ??? Subunits Activate the Muscarinic K+ Channel in Bullfrog Atrial Myocytes. FASEB J 7(7):A1138 (April 1993).
Marshall LA, Murphy J, Marinari L, Chang J: Characterization and Pharmacological Modulation of Soluble Phospholipase A2 Generated During Glycogen-Induced Rat Peritonitis. Agents Actions 37:60-69 (1992).
St. Joseph's University: B.S. Biology 1989
University of Virginia : Ph. D. Physiology 1997
George Washington University Law School: J.D. 2005
United States Patent and Trademark Office, Alexandria, VA
Patent Examiner 1999-2005
Message Pharmaceuticals, Inc., Malvern, Pennsylvania Post-Doctoral Scientist, In Vitro Assay Development (developed assays for secondary screening of compounds that target RNA; these assays include an ELISA assay, an in vitro translation assay utilizing luciferase as a reporter gene, and a Ribosome Display assay for identification of novel peptides that bind) RNA, 1997-1999
A.I. DuPont Institute, Wilmington, Delaware, Post-Doctoral Fellowship, Epithelial Cell Biology Laboratory (Examined the role of phosphorylation in the regulation of the Cystic Fibrosis Transmembrane Conductance Regulator utilizing two-electrode voltage clamp of Xenopus oocytes expressing CFTR. Investigated the function of a novel compound that increases the phosphorylation of CFTR), 1996-1997
University of Virginia, Charlottesville, Virginia Graduate Fellowship,
Department of Molecular Physiology and Biological Physics - Studied the regulation of the muscarinic K+ channel by G proteins utilizing the single channel patch clamp technique. Examined the role of phosphorylation in the regulation of the cloned form of the muscarinic K+ channel. 1989-1996
Wyeth-Ayerst Research, Princeton, New Jersey Internship (Examined the changes in soluble PLA2 activity in induced rat peritonitis), summer 1988
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JOSEPH FRANCIS MURPHY, PH. D. PARTNER
INDUSTRIES SERVED
Biotechnology
Biology
Educational and Research Institutions
Pharmaceutical
ADMITTED TO PRACTICE
Pennsylvania
U.S. Patent and Trademark Office
U.S. Court of Appeals for the Federal Circuit
EDUCATIONAL
BACKGROUND
St. Joseph's University: B.S. Biology 1989
University of Virginia : Ph. D. Physiology 1997
George Washington University Law School: J.D. 2005
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